Many drug substances are insoluble and have poor bioavailability in the human body. One of our core strategies is to apply our unique nano technology to improve the solubility. This technology is able to significantly reduce the drug particle size to the nano scale through a process of recrystallization, milling, and introduction of stabilizers, coupled with our innovative nano coating technology. With our nano scale controlled release drug delivery system, we are able to improve drug bioavailability, consequently enhance therapeutic efficacy. Currently, we have obtained positive experimental data by applying our novel drug delivery system to animal models.